Inflammatory Bowel Disease Clinical Care Pathways

Initiation of Immunomodulators (Thiopurines and Methotrexate)

This IBD clinical care pathway provides a guideline for health care providers when initiating immunomodulators (thiopurines and methotrexate) and its use in adults with inflammatory bowel disease.

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Disclaimer: Clinical care pathways are not a substitute for the personalized judgement and care of a trained healthcare professional. 

Clare McCabe Woodrow (Alberta Health Services) and Dr. Natasha Bollegala (Women’s College Hospital & University of Toronto) led the review and update for the current version of this IBD Clinical Care Pathway.

Additional resources

For IBD Providers

• Harvey Bradshaw Index 
• Partial Mayo Scoring Index
• Therapy decision tree for Crohn’s disease
• Therapy decision tree for ulcerative colitis

For People with IBD

• Azathioprine or 6-Mercaptopurine (6-MP) for IBD
• Taking Azathioprine 
• Taking 6-Mercaptopurine (6-MP) 
• Methotrexate patient information sheets
• Methotrexate for IBD 
• Taking Methotrexate

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